Two casualties were cut free from a car following a collision south of Ludlow on Monday afternoon.
The collision involving an HGV livestock transporter and a car happened on the B4361 in Overton.
A grey Honda CR-V was travelling on the B4361 towards the junction with Overton Road when it was involved in a collision with a lorry travelling northbound.
A passenger of the car sustained serious injuries and was airlifted to Queen Elizabeth Hospital, Birmingham.
The driver of the car was taken to Hereford County Hospital with minor injuries.
A spokesperson for West Midlands Ambulance Service said: “We were called at 2.52pm to reports of a road traffic collision between a car and livestock vehicle on the B4361 in Overton.
“We have treated the passenger of the car for potentially serious injuries and she has been airlifted to the Queen Elizabeth Hospital in Birmingham for further treatment.
“The driver of the car has been treated for injuries not believed to be serious and he has been conveyed to Hereford County Hospital via land ambulance.”
Shropshire Fire and Rescue Service released the man and woman from the car using holmatro cutting equipment.
Five fire appliances were mobilised from Craven Arms, Ludlow and Wellington with an operations officer also in attendance.
Two air ambulances, West Midlands Ambulance Service and West Mercia Police also attended.